Table 2.

Executive function, processing speed, and episodic memory Z-score in adults with Down syndrome across 12 months by intervention arm. Cohen’s d values represent standardized between-group differences in longitudinal change estimated from mixed models.

	Remote High (RH)		Remote Low (RL)		Support/Education (SE)		Effect sizes (Cohen’s d)
	n	Mean ± SD	n	Mean ± SD	n	Mean ± SD
Executive function
Baseline	32	0.012±0.363	29	−0.025±0.393	12	0.066±0.398	—
6-months	32	−0.002±0.387	27	0.030±0.401	12	−0.058±0.551	SE-RH= −0.08
							SE-RL= −0.13
							RH-RL= −0.06
12-months	32	0.007±0.410	25	0.038±0.393	11	−0.099±0.473	SE-RH= −0.15
							SE-RL= −0.21
							RH-RL= −0.06
Processing speed
Baseline	32	0.132±0.690	29	−0.180±1.108	12	−0.036±1.010	—
6-months	32	0.184±0.512	27	0.114±0.600	12	0.168±0.521	SE-RH= 0.07
							SE-RL= −0.02
							RH-RL= −0.09
12-months	32	0.245±0.465	25	−0.024±0.865	11	0.172±0.497	SE-RH= 0.05
							SE-RL= 0.22
							RH-RL= 0.17
Episodic memory
Baseline	32	0.070±1.039	29	−0.126±0.956	12	0.019±0.899	—
6-months	32	0.219±1.018	27	−0.247±0.925	12	0.676±0.836	SE-RH= −0.05
							SE-RL= 0.19
							RH-RL= 0.24
12-months	32	0.175±0.976	25	0.127±1.058	11	0.108±0.827	SE-RH= 0.07
							SE-RL= 0.08
							RH-RL= 0.01