Table 4.
Tumor characteristics of the 909 breast tumors from 866 breast cancer patientsanalyzed for the BACH1 Ser919Pro variant.
| BACH1 Ser919Pro | |||||
| Total n (%) | Pro/Pro | Pro/Ser | Ser/Ser | p | |
| Histology | 909 | ||||
| Carcinoma ductale | 713 (78.4) | 145 (76.3) | 358 (78.7) | 210 (79.5) | 0.480 |
| Carcinoma lobulare | 130 (14.3) | 25 (13.2) | 70 (15.4) | 35 (13.3) | |
| Carcinoma medullare | 13 (1.4) | 5 (2.6) | 5 (1.1) | 3 (1.1) | |
| Other | 53 (5.8) | 15 (7.9) | 22 (4.8) | 16 (6.1) | |
| Tumor grade | 817 | ||||
| 1 | 223 (27.3) | 51 (29.8) | 116 (28.2) | 56 (23.9) | 0.702 |
| 2 | 353 (43.2) | 73 (42.7) | 174 (42.2) | 106 (45.3) | |
| 3 | 241 (29.5) | 47 (27.5) | 122 (29.6) | 72 (30.8) | |
| Tumor size, pT | 887 | ||||
| 1 | 545 (61.4) | 121 (65.8) | 269 (60.7) | 155 (59.6) | 0.423 |
| 2 | 282 (31.8) | 47 (25.5) | 148 (33.4) | 87 (33.5) | |
| 3 | 31 (3.5) | 7 (3.8) | 15 (3.4) | 9 (3.5) | |
| 4 | 29 (3.3) | 9 (4.9) | 11 (2.5) | 9 (3.5) | |
| Lymph node status, pN | 909 | ||||
| Negative | 477 (52.5) | 104 (54.7) | 223 (49.0) | 150 (56.8) | 0.101 |
| Positive | 432 (47.5) | 86 (45.3) | 232 (51.0) | 114 (43.2) | |
| Distant Metastasis, pM | 870 | ||||
| Negative | 829 (95.3) | 168 (93.9) | 416 (96.1) | 245 (95.0) | 0.478 |
| Positive | 41 (4.7) | 11 (6.1) | 17 (3.9) | 13 (5.0) | |
| Estrogen receptor status | 862 | ||||
| Positive | 680 (78.9) | 139 (76.8) | 339 (78.5) | 202 (81.1) | 0.530 |
| Negative | 182 (21.1) | 42 (23.2) | 93 (21.5) | 47 (18.9) | |
| Pogesterone receptor status | 863 | ||||
| Positive | 591 (68.5) | 129 (70.9) | 289 (66.9) | 173 (69.5) | 0.577 |
| Negative | 272 (31.5) | 53 (29.1) | 143 (33.1) | 76 (30.5) | |