Table 1.

Summary of SCC Tumors

Patient #	Stage	Grade	HIF-1α Score	HIF-1α P/M	TSC1/2 P/M	vHL P/M
1	2	WD	2	NC	Exon 41(TSC2), P/G5346C	NC
2	3	UD	1	NC	NC	NC
3	2	WD	3	NC	NC	NC
4	1	WD	2	NC	Exon 41(TSC2), P/G5346C	NC
5	2	MD	3	Exon 12, P/C1772T	Exon 41(TSC2), P/G5346C	NC
6	4	UD	2	NC	NC	NC
7	1	WD	1	NC	Exon 41(TSC2), P/G5346C	NC
8	2	WD	4	NC	NC	NC
9	1	WD	1	NC	Exon 41(TSC2), P/G5346C	NC
10	2	MD	3	NC	NC	NC
11	3	WD	3	Exon 12, P/C1772T	Exon 41(TSC2), P/G5346C	NC
12	2	MD	1	NC	Exon 41(TSC2), P/G5346C	NC
13	1	WD	1	NC	NC	NC
14	1	WD		NC	NC	NC
15	3	MD	3	Exon 12, P/G1790A	NC	NC
16	2	MD	1	NC	NC	NC
17	2	WD	2	NC	NC	NC
18	2	WD	3	NC	Exon 40 (TSC2) 528_5255 del	NC
19	1	WD	2	NC	NC	NC
20	4	MD	2	NC	NC	NC
21	3	WD	3	Exon 12, P/G1790A	NC	NC
22	2	WD	1	NC	NC	NC
23	2	WD	1	NC	NC	NC
24	3	WD	2	NC	NC	NC
25	4	MD	2	NC	NC	NC
26	2	MD	3	Exon 12, P/C1772T	NC	NC
27	2	WD	2		NC	NC
28	3	WD	4	Exon 12, M/C1771A	Exon 36 (TSC2) 4681 delAG 40 (TSC2) 5238_5255 del 41(TSC2) P/G5346C	NC

WD-Well differentiated;MD-Moderately Well-differentiated; UD-Undifferentiated;NC-No change wild-type; P-polymorphism; M-Mutation; del-deletion