Table 3.
Quantile g-computation estimates of adjusted mean differences (ψ) in MSEL Composite scores and T-scores of subscales of children at 6, 12, 24, and 36 months of age in association with a simultaneous one-tertile increase in prenatal maternal urinary concentrations of six OPE biomarkers detected in ≥60% of samples.
| MSEL | 6 months | 12 months | 24 months | 36 months |
|---|---|---|---|---|
| β (95% CI) | β (95% CI) | β (95% CI) | β (95% CI) | |
|
| ||||
| Composite | 1.24 (−3.02, 5.50) | 2.76 (−1.93, 7.44) | −0.50 (−6.60, 5.61) | −2.03 (−9.13, 5.07) |
| Fine Motor | 0.25 (−2.92, 3.42) | 1.61 (−1.90, 5.12) | −0.11 (−3.82, 3.59) | −0.29 (−5.12, 4.53) |
| Visual Reception | −1.22 (−5.17, 2.73) | 2.62 (−0.34, 5.58) | −0.89 (−4.91, 3.13) | 1.87 (−3.19, 6.93) |
| Receptive Language | 3.51 (−0.30, 7.31) | 1.52 (−1.86, 4.89) | −0.07 (−4.97, 4.83) | −1.51 (−5.28, 2.25) |
| Expressive Language | −0.22 (−2.72, 2.27) | −0.26 (−3.97, 3.44) | 0.01 (−3.51, 3.52) | −4.01 (−7.80, −0.21) |
Note: All models were adjusted for child sex, child year of birth, homeownership, maternal age at delivery, maternal education, parity, maternal pre-pregnancy body mass index (BMI), and maternal race/ethnicity. Bolded numbers indicate p-values < 0.05.