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. 2026 Oct 9;10:e97392. doi: 10.2196/97392

Table 3.

Exploratory baseline-to-final changes in psychological and physical health outcomes.


Exercise (n=4) Control (n=2)
Variables Baseline median (min-max)a Final median (min-max) Baseline median (min-max) Final median (min-max)
Depression 2.5 (1-13) 7.5 (2-13) 15 (8-22) 9.5 (7-12)
Anxiety 3 (1-12) 6 (2-20) 15.5 (15-16) 12 (11-13)
Stigma 2.9 (1-4.7) 2.5 (1-5.6) 3.3 (3.2-3.4) 3.8 (3.6-3.9)
General self-efficacy 3.6 (2.5-4.1) 3.5 (3.4-4) 2.9 (1.8-4) 3.4 (3.1-3.8)
Sleep 5.5 (4-10) 7 (2-9) 9.5 (3-16) 10.5 (4-17)
VO2 max (ml/kg/min) 39.1 (21-54.4) 39.9 (23.9-50.2) 36.3 (32-40.7) 35.9 (32.8-39.1)
Weight (lbs) 175.5 (148.5-211.8) 172.9 (153.8-211.4) 136 (135-137) 130.2 (128-132.4)
BMI (kg/m2) 24.9 (22.1-36.8) 24.5 (22.9-37.4) 21.4 (21.4-21.5) 20.9 (20.1-21.6)
Body fat % 16 (10.2-41) 16.7 (11.3-42.1) 22.4 (21.9-22.9) 20.9 (18.9-22.9)
Habit Index
Instigation subscale 1.5 (1-3) 3 (2-3.3) 1.3 (1-1.7) 1 (1-1)
Preparation subscale 3.5 (1-4) 3.3 (2.3-4.3) 1.5 (1.3-1.7) 1 (1-1)
QOLIE-31b
Seizure worry 79.3 (68.7-95) 86.3 (28.7-96) 54.7 (36.7-72.6) 54.5 (27.3-81.7)
Overall QOL 72.5 (40-77.5) 71.3 (27.5-77.5) 57.5 (37.5-77.5) 63.8 (60-67.5)
Emotional well-being 58 (36-88) 58 (28-80) 40 (24-56) 56 (52-60)
Medication effects 54.2 (33.3-88.9) 23.6 (0-100) 66.7 (61.1-72.3) 69.5 (50-88.9)
Energy and fatigue 47.5 (30-75) 45 (10-55) 30 (10-50) 45 (35-55)
Cognitive function 36.2 (10-80) 43.6 (3.3-93.3) 24.3 (19.7-28.9) 37.6 (25.6-49.7)
Social function 93 (81-100) 92.5 (28-100) 65 (35-95) 78.5 (62-95)
Total QOLIE-31 64 (39.8-81.5) 63.7 (18.6-81.8) 44.2 (30.7-57.8) 55.6 (48.9-62.2)

aData are presented as median (minimum-maximum) because of the small group sample size.

bQOLIE-31: Quality of Life in Epilepsy Inventory-31.