Table 2.
Psychiatric comorbidities of the study population by outcomes in OAT
| Psychiatric condition | Overall | Self-harm | Drug overdose | Death | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N = 1,235 | no | yes | p value1 | no | yes | p value1 | no | yes | p value2 | |
| N = 956 | N = 279 | N = 935 | N = 300 | N = 1,064 | N = 171 | |||||
| N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | ||||
| Non-SUD psychiatric disorders | 482 (39.0) | 311 (32.5) | 171 (61.3) | <0.001 | 303 (32.4) | 179 (59.7) | <0.001 | 416 (39.1) | 66 (38.6) | 0.901 |
| Any psychosis | 210 (17.0) | 116 (12.1) | 94 (33.7) | <0.001 | 110 (11.8) | 100 (33.3) | <0.001 | 189 (17.8) | 21 (12.3) | 0.077 |
| Psychotic disorders | 172 (13.9) | 101 (10.6) | 71 (25.4) | <0.001 | 96 (10.3) | 76 (25.3) | <0.001 | 157 (14.8) | 15 (8.8) | 0.036 |
| Any SIP | 96 (7.8) | 43 (4.5) | 53 (19.0) | <0.001 | 35 (3.7) | 61 (20.3) | <0.001 | 83 (7.8) | 13 (7.6) | 0.928 |
| Any mood disorder | 360 (29.1) | 244 (25.5) | 116 (41.6) | <0.001 | 246 (26.3) | 114 (38.0) | <0.001 | 310 (29.1) | 50 (29.2) | 0.978 |
| Any depression | 299 (24.2) | 206 (21.5) | 93 (33.3) | <0.001 | 206 (22.0) | 93 (31.0) | 0.002 | 256 (24.1) | 43 (25.1) | 0.758 |
| Any bipolar | 68 (5.5) | 45 (4.7) | 23 (8.2) | 0.023 | 45 (4.8) | 23 (7.7) | 0.059 | 56 (5.3) | 12 (7.0) | 0.351 |
| Any anxiety disorder | 323 (26.2) | 223 (23.3) | 100 (35.8) | <0.001 | 222 (23.7) | 101 (33.7) | <0.001 | 290 (27.3) | 33 (19.3) | 0.028 |
| Any PD | 256 (20.7) | 152 (15.9) | 104 (37.3) | <0.001 | 155 (16.6) | 101 (33.7) | <0.001 | 226 (21.2) | 30 (17.5) | 0.268 |
| Antisocial PD | 127 (10.3) | 67 (7.0) | 60 (21.5) | <0.001 | 68 (7.3) | 59 (19.7) | <0.001 | 113 (10.6) | 14 (8.2) | 0.331 |
| Borderline PD | 131 (10.6) | 78 (8.2) | 53 (19.0) | <0.001 | 79 (8.4) | 52 (17.3) | <0.001 | 120 (11.3) | 11 (6.4) | 0.056 |
| Other SUDs | 758 (61.4) | 525 (54.9) | 233 (83.5) | <0.001 | 510 (54.5) | 248 (82.7) | <0.001 | 652 (61.3) | 106 (62.0) | 0.859 |
| Alcohol | 281 (22.8) | 172 (18.0) | 109 (39.1) | <0.001 | 171 (18.3) | 110 (36.7) | <0.001 | 220 (20.7) | 61 (35.7) | <0.001 |
| Cannabis | 169 (13.7) | 111 (11.6) | 58 (20.8) | <0.001 | 108 (11.6) | 61 (20.3) | <0.001 | 156 (14.7) | 13 (7.6) | 0.013 |
| Sedative | 454 (36.8) | 277 (29.0) | 177 (63.4) | <0.001 | 270 (28.9) | 184 (61.3) | <0.001 | 406 (38.2) | 48 (28.1) | 0.011 |
| Stimulant | 333 (27.0) | 192 (20.1) | 141 (50.5) | <0.001 | 184 (19.7) | 149 (49.7) | <0.001 | 299 (28.1) | 34 (19.9) | 0.025 |
| Multidrug | 260 (21.1) | 132 (13.8) | 128 (45.9) | <0.001 | 128 (13.7) | 132 (44.0) | <0.001 | 222 (20.9) | 38 (22.2) | 0.686 |
PD, personality disorder; SUD, substance use disorder; SIP, substance-induced psychosis; other SUDs, other substance use disorders not related to opioids.
1
Pearson’s chi-squared test.
2
Pearson’s chi-squared test; Fisher’s exact test.