Table III. BSE and vCJD transmissions to inbred lines of mice.
Inoculum |
SJL/OlaHsd |
RIIIS/J |
FVB/NHsd |
C57BL/6/OlaHsd |
||||
---|---|---|---|---|---|---|---|---|
Incubation time (days ± SEM) | Clinical signs | Incubation time (days ± SEM) | Clinical signs | Incubation time (days ± SEM) | Clinical signs | Incubation time (days ± SEM) | Clinical signs | |
BSE (I783) |
196 ± 13 |
25/40 |
241 ± 15 |
20/29 |
589 ± 21 |
22/31 |
710 ± 15 |
6/25 |
vCJD (I336) | 139 ± 17 | 6/10 | 342 ± 31 | 8/8 | ||||
vCJD (I344) | 256 ± 46 | 5/7 | 402 ± 34 | 7/8 | ||||
vCJD (I342) | 169, 169 | 2/11 | 475 ± 68 | 3/10 |