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Fig. 8. Schematic depiction of modification defects in mitochondrial tRNAs for Leu(UUR) and Lys caused by point mutations related to the mitochondrial encephalomyopathies MELAS (nucleotide positions 3243 or 3271) and MERRF (8344), and possible relationship between taurine dietary deficiency and speculated modification impairment as a cause of cardiomyopathy in the cat. U+ stands for a putative intermediate of τm5(s2)U.
