TABLE 2.
Inhibition of Ad37 attachment to Chang C cells by sialylated glycoproteinsa
Glycoprotein | Glycoprotein ID50 (μM) | % Maximal inhibition of Ad37 attachment at 500 μM glycoprotein |
---|---|---|
BSAb | >500 | 0d |
Fetuin | 420 | 62 |
Asialofetuin | >500 | 10 |
Mucinc | 8 | 89 |
Asialomucinc | >500 | 0 |
Orosomucoid | 75 | 77 |
Glycophorin A | >500 | 45 |
Determined as described in Materials and Methods. Each value represents the mean from three independent experiments.
BSA, bovine serum albumin.
The molecular mass of mucins has not yet been accurately determined and was estimated here to be 200 kDa.
Determined at 3 mM.