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Relative infectivities of Ad5Luc.NNRGD viruses. Infectious titers of the purified viruses were determined in a spot assay on 293 cells and were then compared to that of the Ad5Luc1 control vector incorporating unmodified Ad5 fibers. Bars represent infectious unit/viral particle ratios for Ad5Luc.NNRGD vectors divided by the ratio obtained for Ad5Luc1 (wt). Numbers at the bottom show the sizes of the penton base-derived polypeptides incorporated into the HI loop of a given Ad vector.
