TABLE 1.
Features of proteins of LV strains 145SL and 174F and the prototype strain 87-012a
| Protein | No. of amino acids in protein of strain:
|
Amino acid positions for the prototype protein | Predicted activity or function of viral protein | ||
|---|---|---|---|---|---|
| 145SL | 174F | 87-012 | |||
| VP0 | 259 | 259 | 259 | 1Met-Gln259 | Capsid protein |
| VP3 | 244 | 244 | 244 | 260Gly-Gln503 | Capsid protein |
| VP1 | 297 | 297 | 297 | 504Gly-Glu800 | Capsid protein |
| 2A1 | 20 | 20 | 20 | 801Met-Gly820 | Primary polyprotein processing |
| 2A2 | 135 | 135 | 135 | 821Pro-Gln955 | Inhibition of cell growth |
| 2B | 140 | 138 | 138 | 956Ser-Glu1093 | Membrane associated |
| 2C | 334 | 333 | 333 | 1094Gly-Asn1426 | ATPase |
| 3A | 130 | 130 | 130 | 1427Glu-Glu1556 | Membrane associated |
| 3B | 29 | 29 | 29 | 1557Arg-Glu1585 | Initiation of RNA synthesisb |
| 3C | 198 | 198 | 198 | 1586Ala-Gln1783 | Protease |
| 3D | 470 | 470 | 470 | 1784Gly-Asp2253 | RNA-dependent RNA polymerase |
The polyproteins of strains 145SL, 174F, and 87-012 contain 2,256, 2,253, and 2,253 amino acids in all, respectively.
Protein 3BVPg.