| CTCs | Circulating tumor cells |
| PD-L1 | programmed cell death-ligand 1 |
| EVs | extracellular vesicles |
| NSCLC | non-small cell lung cancer |
| SCLC | small cell lung cancer |
| ORR | objective response rate |
| PD | Disease progression |
| SD | Stable disease |
| PR | Partial response |
| ROC | receiver operating characteristic curves |
| WES | whole-exome sequencing |
| ICIs | immune checkpoint inhibitors |
| TMB | tumor mutation burden |
| AUC | area under the curve |
| PFS | progression-free survival |
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