ccRCC	clear cell renal cell carcinoma
VHL	von Hippel–Lindau
HIF	hypoxia-inducible factor
VEGF	vascular endothelial growth factor
PDGF	platelet-derived growth factor
mTORC1	mechanistic target of rapamycin complex 1
mTORC2	mechanistic target of rapamycin complex 2
TSC1	tuberous sclerosis complex 1
TSC2	tuberous sclerosis complex 2
AMPK	AMP-activated protein kinase
ER	endoplasmic reticulum
UPR	unfolded protein response
REDD1	regulated in development and DNA damage responses 1
VCP	valosin-containing protein
ERAD	endoplasmic reticulum-associated degradation
PERK	protein kinase R-like endoplasmic reticulum kinase
IRE1α	inositol-requiring enzyme 1α
ATF6	activating transcription factor 6
ATF4	activating transcription factor 4
GRP78	glucose-regulated protein 78
BiP	binding immunoglobulin protein
XBP1	X-box binding protein 1
eIF2α	eukaryotic translation initiation factor 2α
CHOP	C/EBP homologous protein
TXNIP	thioredoxin-interacting protein
ROS	reactive oxygen species
ATM	ataxia-telangiectasia mutated
S6K1	ribosomal protein S6 kinase 1
4EBP1	eukaryotic translation initiation factor 4E-binding protein 1
PP2A	protein phosphatase 2A
Rheb	Ras homolog enriched in brain
PLK1	Polo-like kinase 1
MAMs	Mitochondria-associated endoplasmic reticulum membranes
IP3R	inositol 1,4,5-trisphosphate receptor
VDAC	voltage-dependent anion channel