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Demonstration of TNF-α transcripts in paraffin-embedded sections of brain from an SIV-infected macaque with SIVE. Many TNF-α+ cells are CD68+ macrophages (colocalized as yellow) located within a focus of inflammation. TNF-α transcripts are also evident within endothelial cells adjacent to the lesion and other cells within the neuropil. Bar = 10 μm.
