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(A) General strategy for creation of an allosteric ribozyme (aptazyme), depicting the aptamer, communication, and ribozyme modules. The order of events starting with ligand binding is numbered. (B) Specific example of an allosteric ribozyme that is sensitive to flavin mononucleotide (FMN; Soukup and Breaker 1999b). (C) The general communication module of Kertsburg and Soukup (2002).
