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Influence of Ψ39 and Ψ55 on frameshifting at U-UUU-UUA and A-AAA-AAC sites. (A) In the truA mutant, all tRNAs, reading codons at slippery sites, contain U39 instead of Ψ39. (B) In the truB mutant, all tRNAs, reading codons at slippery sites, contain U55 instead of Ψ55. The frequency of frameshifting is expressed as the β-galactosidase activity normalized to the β-lactamase activity normalized encoded by the bla gene present on the same plasmid as that encoding the lacZ gene.
