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. 2003 Oct;9(10):1246–1253. doi: 10.1261/rna.5113603

FIGURE 3.

FIGURE 3.

Secondary structure of the frameshift stimulatory signal of all of the subtypes of HIV-1 group M. The frameshift stimulatory region is folded according to the extended bulged stem–loop structure found for HIV-1 subtype B stimulator (Dulude et al. 2002). Circles indicate nucleotides that differ from subtype B. The arrows point to noncanonical base pairs and mismatches. The thermodynamic stability, ΔG° (kcal/mole), of the frameshift stimulatory signal of the different subtypes is indicated. The predicted ΔG° were calculated as described in the legend to Figure 2.