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. 2026 Oct 14;27(20):9112. doi: 10.3390/ijms27209112
LCT α-Latrocrustatoxin
α-LTX α-Latrotoxin
ADGRL1 Adhesion G protein-coupled receptor L1
ALP Alkaline phosphatase
AST Aspartate aminotransferase
BLI Bio-layer interferometry
cDNA Complementary DNA
CIRL Calcium-independent receptor for α-latrotoxin
cryo-EM Cryo-electron microscopy
CTF C-terminal fragment
DNA Deoxyribonucleic acid
EC50 Half-maximal effective concentration
ED50 Median effective dose
ELISA Enzyme-linked immunosorbent assay
EM Electron microscopy
EPSC Excitatory postsynaptic current
Fab Antigen-binding fragment
F(ab′)2 Bivalent antigen-binding fragment
GABA γ-Aminobutyric acid
GPCR G protein-coupled receptor
IC50 Half-maximal inhibitory concentration
IgG Immunoglobulin G
IM Intramuscular
IP Intraperitoneal
IP3 Inositol 1,4,5-trisphosphate
IV Intravenous
K_D Equilibrium dissociation constant
KLH Keyhole limpet hemocyanin
LD50 Median lethal dose
LD100 Dose producing complete lethality under the stated experimental conditions
LIT Latroinsectotoxin
LMWP Low-molecular-weight peptide
LMWP2 Low-molecular-weight peptide 2
LTX Latrotoxin
mEPSC Miniature excitatory postsynaptic current
MW Molecular weight
NF-κB Nuclear factor κB
NTF N-terminal fragment
pI Isoelectric point
PIP2 Phosphatidylinositol 4,5-bisphosphate
PLC Phospholipase C
RAVE Redback Antivenom Evaluation
RAVE-II Second Redback Antivenom Evaluation study
RPTPσ Receptor-type protein tyrosine phosphatase σ
RT Room temperature
SC Subcutaneous
SDS-PAGE Sodium dodecyl sulfate–polyacrylamide gel electrophoresis
SEC Size-exclusion chromatography
SNAP-25 Synaptosomal-associated protein of 25 kDa
SNARE Soluble N-ethylmaleimide-sensitive factor attachment protein receptor
VAMP Vesicle-associated membrane protein
w/w Weight-to-weight ratio