Table 2.

Clinical and radiological characteristics according to baseline miRNA dysregulation.

Clinicoradiological features			Baseline miRNA expression*
			miR-10a	miR-146a	miR-155
Diagnosis age			0.648	0.769	0.461
Sex			0.992	0.502	0.465
Number of relapses		Baseline	0.806	0.135	0.236
		Final	0.058	0.693	0.270
		Total	0.789	0.288	0.637
ARR		Baseline	0.626	0.179	0.525
		Final	0.253	0.687	0.471
		Total	0.451	0.450	0.998
EDSS		Baseline	0.052	0.527	0.293
		Final	0.007	0.837	0.999
		Increase during follow-up	0.373	0.368	0.345
Radiological Features (MRI)	Baseline	Cortical/Juxtacortical	0.734	0.929	0.872
		Infratentorial	0.827	0.077	0.128
		Cervical	0.040	0.323	0.080
	Follow-up after analysis	Cortical/Juxtacortical	0.841	0.103	0.216
		Periventricular	0.954	0.692	0.306
		Infratentorial	0.644	0.083	0.200
		Cervical	0.227	0.020	0.025
		CEL	0.715	0.217	0.555
		New/Enlarging T2 Lesion	0.632	0.107	0.052

ARR = annualized relapse rate, CEL = contrast-enhancing lesion(s), EDSS = Expanded Disability Status Scale, miR-10a = microRNA 10a, miR-146a = microRNA 146a, miR-155 = microRNA 155, miRNA = microRNA, MRI = magnetic resonance imaging.

^*Log2 2^–∆∆CT, Bold P values are significant (<.05).