TABLE 1.

Conformational transitions in the RNA (K2)

Conformational transition	Bound RNA (MD − LES)	Unbound RNA (MD − LES)	Bound RNA (MD + LES)	Unbound RNA (MD + LES)
Opening of the K-turn Unpaired A30	No	Partial	No	Yes
Syn > high anti/anti C2′-endo > C3′-endo	No	Yes	No	Yes
Loss of G-A base pairs	No	No	No	Yes
Loss of interstrand contacts	No	Yes	No	Yes