| cCR | clinical complete response |
| CI | confidence interval |
| ctDNA | circulating tumor DNA |
| DRE | digital rectal examination |
| DWI | diffusion-weighted imaging |
| HR | hazard ratio |
| iCR | integrated complete response |
| MMR | mismatch repair |
| MRI | magnetic resonance imaging |
| MSI | microsatellite instability |
| TME | total mesorectal excision |
| TNT | total neoadjuvant therapy |