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(A) Cloverleaf structure of tRNAArgmnm5UCU with the mutations discussed in this paper indicated. The C61U mutation was isolated in five independent cases, and one of them is the original mutant sufF44; all the other mutations were obtained once. (B) Tertiary structure of tRNAPhe from yeast (see Kim et al. 1974). The arrows are pointing to the positions of mutated nucleotides.
