. 2005 Aug;11(8):1317–1328. doi: 10.1261/rna.2520405

TABLE 4.

Comparison of concentrations of inhibitors required for 50% inhibition of stable subunits formation from the model PoTC by RRF/EF-G/IF3 under two different conditions

	Concentration required for 50% inhibition of
Inhibitors	(A) Subunits formation from PoTC by RRF/EF-G/IF3 simultaneously^a	(B) Subunits formation from PoTC by pre- incubation with RRF/EF-G, then IF3^b
Thiostrepton	6.0 μM	6.5 μM
Fusidic acid	15.0 μM	20.0 μM
Viomycin	50.0 μM	Not determined

^aEstimated from Figure 4.

^bModel PoTC was first incubated with RRF (1 μM), EF-G (1 μM), and GTP (0.36 mM) for 15 min at 30°C. Then inhibitors and IF3 (4.5 μM) were added.