AITL	Angio-immunoblastic T-cell lymphoma
aKG	a-ketoglutarate
allo-HCT	allogeneic hematopoietic cell transplantation
ADC	antibody–drug conjugate
AP1	activator protein 1
ASCT	autologous stem-cell transplantation
Bcl-6	B-cell lymphoma 6
BM	bone marrow
BV	Brentuximab vedotin
BsAb	bispecific antibodies
BTK	bruton tyrosine kinase
A+CHP	BV plus cyclophosphamide, doxorubicin and prednisone
CAR T	chimeric antigen receptor T-cell
CARD11	a scaffold protein that organizes signaling complexes essential for adaptive immunity
Cas9	CRISPR-associated protein 9
CCL17	CC chemokine ligand 17
CCR4	C-C chemokine receptor type 4
CeO2	cerium oxide
CHOEP	etoposide +CHOP
CHOKA	choline kinase a
CHOP	cyclophosphamide + doxorubicin + vincristine + prednisolone chemo regiment
CPT1	carnitine palmitoyltransférase 1
CR	complete response
CREBBP	CREB binding lysine acetyltransferase
CRISPR	clustered regularly interspaced short palindromic repeats
CTNNB1	Catenin Beta 1
CXCL13	C-X-C motif chemokine ligand 13
CXCR5	C-X-C motif chemokine receptor 5
D2HG	D-2-hydroxyglutarate
DNMT3	DNA methyltransferase
EP300	EP300 Lysine Acetyltransferase
ETC	electron transport chain
EZH2	Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit
Fas	Fas Cell Surface Death Receptor
FDA	U.S. Food and Drug Administration
FDC	follicular dendritic cells
FER	FER tyrosine kinase
FYN	FYN proto-oncogene, Src family tyrosine kinase
GAPDH	glyceraldehyde 3-phosphate dehydrogenase
GC	germinal center
GSEA	gene set enrichment analysis
GTPase	hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP).
HDACi	histone deacetylase inhibitor
HETP	5-Hydroxyethyl 5,3′ thiophenyl pyridine
IC	immune checkpoint
IC50	median inhibitory concentration
ICOS	Inducible T-cell costimulator
IDH2	isocitrate dehydrogenase-2
IKK	IκB kinase
IL-6	interleukin 6
ITK	IL2 Inducible T-Cell Kinase
JAK1/2	janus kinase 1/2
KDM6A	gene Lysine Demethylase 6A
KMT2D	lysine Methyltransferase 2D
LPC	lysophosphatidylcholine
LPCAT1	lysophosphatidylcholine acyltransferase 1
MAPK	mitogen-activated protein kinase
MMAE	microtubule-destroying agent monomethyl auristatin E
mAbs	monoclonal antibodies
mTOR	mechanistic target of rapamycin
NEMO	subunit of the IκB kinase complex that activates NF-κB
NF-κB	nuclear factor kappa-light-chain-enhancer of activated B-cells
NFAT	nuclear factor of activated T-cells activator protein 1
NFAT	nuclear factor of activated T-cells
NIK	NF-κB-inducing Kinase
NK	natural killer cell
NP	nanoparticle
ORR	objective response rate
OS	overall survival
OT-II mice	a genetically engineered, transgenic mouse strain widely used in immunology research to study CD4+ helper T-cell responses
OXPHOS	oxidative phosphorylation
PA	phosphatidic acid
PC	phosphatidyl choline
PD-1	programmed cell death protein 1
PDL1	programmed death-ligand 1
PFS	progression-free survival
PI3K	phosphatidylinositol 3-kinase
PLCG1	phospholipase C gamma 1
PLD	phospholipases D
PTCL-NOS	peripheral T-cell lymphoma not otherwise specified
PTCL	peripheral T-cell lymphoma
R/R	relapsed or refractory
RHOA	ras homolog family member A
ROS	reactive oxygen species
STAT	signal transducers and activators of transcription
SYK	Associated Tyrosine Kinase
TBK1	TANK-binding kinase 1
TCR	T-cell receptor
TET2	ten-eleven translocation-2
Tfh	follicular helper T-cells
TIL	tumor-infiltrating lymphocytes
TME	tumor microenvironment
TRBC1	T-cell receptor (TCR) β-chain constant region 1
VAV1	vav guanine nucleotide exchange factor 1
VEGF	vascular endothelial growth factor
WHO	World Health Organization