TABLE 1.

Prediction accuracies and number of positive and negative samples in the training, testing, and independent evaluation set of rRNA-, mRNA-, tRNA-, and snRNA-binding proteins and of all RNA-binding proteins

	Training set		Testing set				Independent evaluation set
			positive		negative		positive			negative
Protein family	positive	negative	TP	FN	TN	FP	TP	FN	SE (%)	TN	FP	SP (%)	Q (%)
RNA-binding	2161	2965	1844	6	6802	14	437	10	97.8	4685	196	96.0	96.1
rRNA-binding	708	972	1243	2	9031	13	95	6	94.1	4931	66	98.7	98.6
mRNA-binding	277	2106	129	0	10164	0	130	34	79.3	5833	213	96.5	96.0
tRNA-binding	94	792	114	0	9295	2	48	3	94.1	5028	5	99.9	99.8
snRNA-binding	33	1988	7	0	10373	1	9	11	41.0	6133	18	99.7	99.5

Predicted results are given in TP (true positive), FN (false negative), TN (true negative), FP (false positive), sensitivity SE = TP/(TP + FN), specificity SP = TN/(TN + FP), and Q (overall accuracy, Q = (TN + TP)/(TP + FN + TN + FP)). Number of positive or negative samples in the testing and independent evaluation sets is TP + FN or TN + FP, respectively.