6PPD-Q	6-(N-phenyl-p-phenylenediamine) quinone
PPD	p-Phenylenediamine
PPD-Qs	p-Phenylenediamine quinones
cAMP	Cyclic adenosine monophosphate
BDNF	Brain-derived neurotrophic factor
GPCRs	G protein-coupled receptors
AC	Adenylyl cyclase
PDEs	Phosphodiesterases
ADORA2A	Adenosine A2A receptor
BBB	Blood-brain barrier
CNS	Central nervous system
SPF	Specific pathogen-free
EPM	Elevated plus maze
OFT	Open field test
UPLC-MS/MS	Ultra-performance liquid chromatography-tandem mass spectrometry
TEM	Transmission electron microscopy
H&E	Hematoxylin and eosin
FJB	Fluoro-Jade B
DAPI	4′,6-Diamidino-2-phenylindole
qRT-PCR	Quantitative real-time polymerase chain reaction
PCA	Principal component analysis
DEGs	Differentially expressed genes
GO	Gene Ontology
KEGG	Kyoto Encyclopedia of Genes and Genomes
GSEA	Gene Set Enrichment Analysis
PDB	Protein Data Bank
RMSD	Root-mean-square deviation
RMSF	Root-mean-square fluctuation
Rg	Radius of gyration
SASA	Solvent-accessible surface area
FEL	Free energy landscape
MIE	Molecular initiating event
AOP	Adverse outcome pathway
N2a	Neuro-2a
MEM	Minimum Essential Medium
FBS	Fetal bovine serum
DMSO	Dimethyl sulfoxide
ELISA	Enzyme-linked immunosorbent assay
BCA	Bicinchoninic acid
SDS-PAGE	Sodium dodecyl sulfate-polyacrylamide gel electrophoresis
TBST	Tris-buffered saline with Tween 20
ANOVA	Analysis of variance
LSD	Least significant difference
SD	Standard deviation