Table 1.
Components involved in β-barrel protein insertion
| Prokaryotes | Eukaryotes | ||||||
|---|---|---|---|---|---|---|---|
| Machinery components | Mitochondria | Chloroplasts | |||||
| Primary translocon | Receptors | SecA | Tom20 | Toc34 | |||
| Tom22 | Toc64 | ||||||
| Tom70 | Toc159 | ||||||
| Tom5/6/7 | |||||||
| Pore | SecYEG | Tom40 | Toc75-III | ||||
| IMS machinery | Chaperone system | Skp | Tim8 & Tim13 | Toc12 & imsHsp70 | |||
| SurA | Tim9 & Tim10 | ||||||
| Secondary translocon | Species | Ec | Nm | S | N | ||
| Translocon | YaeT | Omp85 | slr1227 | alr2269 | Sam50/Tob55/mtOmp85 | Toc75-V/Oep80 | |
| Assisting proteins | YfiO | NI | NI | NI | Sam37/Mas37 | NI | |
| YfgL | Sam35/Tob38/Tom38 | ||||||
| NlpB | Mdm10 | ||||||
| Tom13/Mim1 | |||||||
Ec, Escherichia coli; IMS, intermembrane space; N, Nostoc PCC 7210; NI, not yet identified; Nm, Neisseria Meningitides; S, Synechocystis PCC6803; Sam, sorting and assembly of mitochondria outer membrane proteins; Tic, tranlocase on inner membrane of chloroplast; Tim, tranlocase on inner membrane of mitochondria; Tob, topogenesis of mitochondrial outer membrane β-barrel proteins; Toc, tranlocase on outer membrane of chloroplast; Tom, tranlocase on outer membrane of mitochondria. In the case of several names, the nomenclature used in the manuscript is the first term.