Table 3.
Prognosis of 10 patients with neuroblastoma
| Case | Conventional treatment* | Time to first progression or recurrence | Site of first progression or recurrence | Postprogression or recurrence treatment | Prognosis | Survival period (months) |
| 1 | Chemotherapy-surgery-chemotherapy | / | / | / | Tumor-free survival | 62 |
| 2 | Chemotherapy-surgery | 5 months after treatment initiation | Brain, lung, bone marrow, bone, distant lymph nodes, liver | Chemotherapy-surgery† | Death | 17 |
| 3 | Chemotherapy-surgery-chemotherapy | 15 months after treatment initiation | Liver | Chemotherapy | Death | 17 |
| 4 | Chemotherapy-surgery-chemotherapy-surgery‡-radiotherapy-chemotherapy | 16 months after treatment initiation | Liver | Chemotherapy | Death | 28 |
| 5 | Chemotherapy-surgery-chemotherapy | 7 months after treatment initiation | Primary site, bone | Chemotherapy | Death | 12 |
| 6 | Emergency surgery§-chemotherapy-surgery-chemotherapy | 34 months after treatment initiation | Brain | Chemotherapy | Death | 36 |
| 7 | Chemotherapy-surgery-chemotherapy-GD2 immunotherapy | 44 months after treatment initiation | Bone, distant lymph nodes | Chemotherapy-DFMO | Death | 64 |
| 8 | Chemotherapy-surgery-chemotherapy-surgery¶-radiotherapy | 9 months after treatment initiation | Primary site, lung, bone | Chemotherapy | Death | 19 |
| 9 | Chemotherapy | 1 month after treatment initiation | Primary site, lung, liver | Chemotherapy-surgery | Death | 6 |
| 10 | Chemotherapy | 1 month after treatment initiation | Lung | Chemotherapy-surgery-surgery** | Death | 5 |
*Unless otherwise specified, ‘surgery’ refers to resection of the primary tumor.
†Wedge resection of the right middle lobe of the lung.
‡Resection of residual retroperitoneal tumor.
§Microsurgical resection of extradural tumor.
¶Resection of residual retroperitoneal and mediastinal tumors plus dissection of distant lymph nodes.
**Resection of the primary tumor and tumors in the right mediastinum and chest wall.
DFMO, difluoromethylornithine.