TABLE 1.
Primary and sensitivity analyses of AUROC.
| Analysis | n | Pooled AUROC (95% CI) | 95% prediction interval | I2 | tau2 | Model |
|---|---|---|---|---|---|---|
| Primary analysis | 35 | 0.794 (0.751–0.832) | 0.512–0.934 | 99 | 0.395 | REML random effects with Hartung-Knapp CI |
| Excluding PROBAST high risk | 26 | 0.787 (0.748–0.822) | 0.552–0.917 | 99 | 0.272 | REML random effects with Hartung-Knapp CI |
| Excluding AUROC ≥ 0.95 | 32 | 0.770 (0.742–0.797) | 0.585–0.889 | 99 | 0.174 | REML random effects with Hartung-Knapp CI |
Abbreviations: AUROC, area under the receiver operating characteristic curve; CI, confidence interval; I2, proportion of total variability attributable to between-study heterogeneity; PROBAST, Prediction model Risk Of Bias Assessment Tool; REML, restricted maximum likelihood; tau2, estimated between-study variance. n denotes the number of independent study-level estimates included in each analysis.