Table 2.
Quantitative agreement between the Kehua assay and the two imported reference systems, including Pearson correlation, Spearman correlation, Lin’s concordance correlation coefficient and Passing-Bablok regression.
| Comparison | Analyte | n | Pearson r | Spearman r | Lin’s CCC | PB slope | PB intercept |
|---|---|---|---|---|---|---|---|
| Kehua vs Freelite | FLC-κ | 133 | 0.988 | 0.974 | 0.986 | 0.989 | 0.223 |
| Kehua vs Freelite | FLC-λ | 133 | 1.000 | 0.951 | 0.999 | 1.077 | −0.787 |
| Kehua vs Freelite | κ/λ ratio | 133 | 0.999 | 0.825 | 0.983 | 1.022 | 0.018 |
| Kehua vs N Latex | FLC-κ | 122 | 0.991 | 0.978 | 0.984 | 0.870 | 1.063 |
| Kehua vs N Latex | FLC-λ | 122 | 0.995 | 0.953 | 0.569 | 1.138 | 0.230 |
| Kehua vs N Latex | κ/λ ratio | 122 | 0.998 | 0.834 | 0.922 | 0.733 | 0.123 |
CCC, concordance correlation coefficient; PB, Passing-Bablok regression. All P-values for Pearson correlation < 0.001. The reduced CCC for Kehua vs N Latex FLC-λ reflects the influence of a single extreme outlier with FLC-λ > 9–000 mg/L; Pearson correlation, which is on a different scale, remained excellent.