Table 2. Kinetic parameters of AlkA and Endo VIII for Xan^a.

Enzyme	Substrate	Km(nM)	Vmax(nM/min)	Vmax/Kmb (min–1)
AlkA	Xanthine	53 ± 24	0.72 ± 0.04	1.4 × 10–2 (1)
	7-Methylguanine	31 ± 2	2.1 ± 0.4	6.8 × 10–2 (4.9)
Endo VIII	Xanthine	124 ± 33	0.96 ± 0.26	7.6 × 10–3 (1)
	Thymine glycol	47 ± 10	18 ± 5	3.8 × 10–1 (50)

^aThe values are derived from three independent experiments and standard deviations are also indicated.

^bThe values in parentheses indicate relative values of V_max/K_m.