Table 3.
Demographics and baseline characteristics (safety analysis set)
| Parameter | Sequence 1 (N = 32) | Sequence 2 (N = 30) | Sequence 3 (N = 32) | Sequence 4 (N = 31) | Overall (N = 125) |
|---|---|---|---|---|---|
| Age (years) at screening | |||||
| n | 32 | 30 | 32 | 31 | 125 |
| Mean | 30.3 | 35.5 | 30.8 | 35.0 | 32.9 |
| SD | 11.4 | 14.0 | 9.3 | 11.3 | 11.7 |
| Median | 26.5 | 30.5 | 29.5 | 31.0 | 30.0 |
| Minimum | 18 | 19 | 18 | 21 | 18 |
| Maximum | 63 | 65 | 52 | 62 | 65 |
| Sex n (%) | |||||
| Female | 10 (31.3%) | 11 (36.7%) | 18 (56.3%) | 16 (51.6%) | 55 (44.0%) |
| Male | 22 (68.8%) | 19 (63.3%) | 14 (43.8%) | 15 (48.4%) | 70 (56.0%) |
| Race n (%) | |||||
| American Indian or Alaska Native | 1 (3.1%) | 2 (6.7%) | 4 (12.5%) | 0 | 7 (5.6%) |
| Asian | 6 (18.8%) | 4 (13.3%) | 4 (12.5%) | 5 (16.1%) | 19 (15.2%) |
| Black or African American | 3 (9.4%) | 0 | 0 | 0 | 3 (2.4%) |
| Native Hawaiian or other Pacific Islander | 0 | 0 | 0 | 1 (3.2%) | 1 (0.8%) |
| White | 19 (59.4%) | 21 (70.0%) | 22 (68.8%) | 22 (71.0%) | 84 (67.2%) |
| Unknown | 0 | 0 | 0 | 1 (3.2%) | 1 (0.8%) |
| Other | 1 (3.1%) | 2 (6.7%) | 2 (6.3%) | 1 (3.2%) | 6 (4.8%) |
| Multiple | 2 (6.3%) | 1 (3.3%) | 0 | 1 (3.2%) | 4 (3.2%) |
| Ethnicity n (%) | |||||
| Hispanic or Latino | 5 (15.6%) | 7 (23.3%) | 8 (25.0%) | 9 (29.0%) | 29 (23.2%) |
| Not Hispanic or Latino | 25 (78.1%) | 22 (73.3%) | 24 (75.0%) | 22 (71.0%) | 93 (74.4%) |
| Unknown | 2 (6.3%) | 1 (3.3%) | 0 | 0 | 3 (2.4%) |
| BMI (kg/m2) at screening | |||||
| n | 32 | 30 | 32 | 31 | 125 |
| Mean | 24.12 | 25.00 | 25.47 | 25.30 | 24.97 |
| SD | 2.73 | 3.41 | 3.21 | 3.38 | 3.20 |
| Median | 23.85 | 24.50 | 25.00 | 25.40 | 24.50 |
| Minimum | 19.5 | 18.9 | 19.2 | 18.9 | 18.9 |
| Maximum | 30.7 | 31.3 | 31.8 | 31.2 | 31.8 |
BMI body mass index, N number of participants in group, n number of participants with observations, SD standard deviation