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. 2026 Oct 27;12(4):e007443. doi: 10.1136/rmdopen-2026-007443

Table 4. Predictors of RA development and/or treatment intensification in ACPA-negative undifferentiated arthritis—multivariable analysis.

RA development RA development/Treatment intensification
adjOR 95% CI P value adjOR 95% CI P value
Large-joint only versus hand-joint only 0.30 0.04 to 2.36 0.25 1.23 0.49 to 3.14 0.66
Hand+large-joint versus hand-joint only 2.68 1.29 to 5.57 0.008** 3.32 1.77 to 6.24 <0.001***
CRP >0.5 mg/dL 2.18 0.97 to 4.87 0.06 2.43 1.26 to 4.69 0.008**
VAS pain, per mm 1.02 1.00 to 1.04 0.07 1.02 1.00 to 1.03 0.008**

**p<0.01 ***p<0.001

ACPA, anticitrullinated protein autoantibodies; adjOR, adjusted OR; CRP, C reactive protein; RA, rheumatoid arthritis; VAS, visual analogue scale.