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. 2026 Nov 2;17:489–501. doi: 10.18632/oncotarget.28914

Table 4. Multivariate Cox proportional hazards analysis of survival factors in the PROS1 mutation group.

Characteristic HR 95% CI p-value
Age_at_diagnosis 1 0.99, 1.01 >0.9
Gender
 Female — —
 Male 1.01 0.88, 1.18 0.8
Race_new
 White — —
 Black or African American 1.2 0.94, 1.53 0.2
 Other 0.85 0.67, 1.07 0.2
Stage
 Stage I — —
 Stage II 1.89 1.59, 2.26 <0.001
 Stage III 2.12 1.76, 2.56 <0.001
 Stage IV 1.62 1.18, 2.22 0.003
Tissue_or_organ_of_origin
 Lower lobe, lung — —
 Lung, NOS 0.72 0.49, 1.06 0.1
 Middle lobe, lung 1.34 0.94, 1.90 0.11
 Upper lobe, lung 1.18 1.01, 1.39 0.034
Treatment_type2
 Chemotherapy — —
 Ancillary Treatment 1.55 0.49, 4.91 0.5
 Immunotherapy (Including Vaccines) 2.41 0.76, 7.59 0.13
 Pleurodesis, NOS — —
 Radiation 1.04 0.88, 1.23 0.6
 Targeted Therapy 0.98 0.81, 1.18 0.8
Laterality
 Left — —
 Right 1.2 1.04, 1.39 0.014
Counts 0.99 0.94, 1.05 0.7

Survival analysis in PROS1 mutation group (Multivariable).