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. 2026 Nov 2;17:489–501. doi: 10.18632/oncotarget.28914

Table 8. Multivariate Cox proportional hazards analysis of survival factors in the F2 mutation group.

Characteristic HR 95% CI p-value
Age_at_diagnosis 1 0.99, 1.01 >0.9
Gender
 Female — —
 Male 0.96 0.78, 1.18 0.7
Race_new
 White — —
 Black or African American 1.06 0.79, 1.41 0.7
 Other 1.39 0.98, 1.96 0.065
Stage
 Stage I — —
 Stage II 1.85 1.46, 2.35 <0.001
 Stage III 2.19 1.68, 2.84 <0.001
 Stage IV 1.6 1.02, 2.50 0.04
Tissue_or_organ_of_origin
 Lower lobe, lung — —
 Lung, NOS 0.88 0.53, 1.45 0.6
 Middle lobe, lung 1.33 0.81, 2.19 0.3
 Upper lobe, lung 1.2 0.97, 1.49 0.092
Treatment_type2
 Chemotherapy — —
 Ancillary Treatment 1.11 0.26, 4.79 0.9
 Immunotherapy (Including Vaccines) 1.5 0.47, 4.83 0.5
 Pleurodesis, NOS — —
 Radiation 0.86 0.68, 1.09 0.2
 Targeted Therapy 0.86 0.66, 1.12 0.3
Laterality
 Left — —
 Right 1.24 1.01, 1.51 0.04
Counts 1.07 1.00, 1.14 0.051

Survival analysis in F2 mutation group (Multivariable).