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. Author manuscript; available in PMC: 2026 Nov 3.
Published before final editing as: Nat Ment Health. 2026 Oct 28:10.1038/s44220-026-00753-y. doi: 10.1038/s44220-026-00753-y

Table 2.

Adjusted Likelihood of Meeting Criteria for Items on the AMHART

Measure Adjusted Odds Ratio 95% CI P-Value

Model
 ChatGPT-5 Ref Ref Ref
 ChatGPT-4 0.69 0.53, 0.90 0.006
 Gemini 2.5 Flash 0.81 0.62, 1.05 0.107
 Claude Sonnet 4.5 0.27 0.21, 0.35 < 0.001
Vignette
 Anxiety Ref Ref Ref
 Depression 0.25 0.21, 0.30 < 0.001
Symptom Severity
 Moderate Ref Ref Ref
 Severe 0.51 0.42, 0.61 < 0.001

Table Notes: “Ref” denotes the regression comparison category used to parameterize a predictor; it does not indicate evaluator weighting or a reference standard for AMHART scoring. Values reported from item-level mixed-effects logistic regression. The binary outcome was whether a given item passed or failed for a particular chatbot-persona-conversation combination, with fixed effects for chatbot, diagnostic category, symptom severity, and sex, and random effects for item and conversation (i.e., run index).