Table 2.

King's College Hospital criteria for liver transplantation in acetaminophen-induced acute liver failure

Current criteria [11]	Modified criteria [14]
List for transplantation if:	Strongly consider listing for transplantation if:
Arterial pH <7.3 after adequate fluid resuscitation	Arterial blood lactate concentration >3.5 mmol/l after early fluid resuscitation
List for transplantation if all three of the following occur within a 24-h period:	List for transplantation if:
• Creatinine >300 μmol/l	Arterial pH <7.3, or arterial blood lactate concentration >3.0 mmol/l after adequate fluid resuscitation
• PT >100 s (INR >6.5)
• Grade III/IV encephalopathy	List for transplantation if all three of the following occur within a 24-h period:
	• Creatinine >300 μmol/l
	• PT >100 s (INR >6.5)
	• Grade III/IV encephalopathy

INR = International Normalized Ratio; PT = prothrombin time.