Table 2.
Cox regression analysis.
| Variable | Univariate analysis | Multivariate analysis-A (without CARMN) | Multivariate analysis-B (with CARMN) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | HR | 95% CI | P | |
| Gender | 1.323 | 0.795–2.200 | 0.281 | - | - | - | |||
| BMI | 1.007 | 0.922–1.099 | 0.880 | - | - | - | |||
| Smoking | 0.804 | 0.427–1.513 | 0.499 | - | - | - | |||
| Hypertension | 1.223 | 0.682–2.195 | 0.500 | - | - | - | |||
| TC | 1.208 | 0.837–1.745 | 0.313 | - | - | - | |||
| TG | 0.613 | 0.213–1.766 | 0.365 | - | - | - | |||
| HDL-C | 0.897 | 0.359–2.240 | 0.815 | - | - | - | |||
| LDL-C | 0.986 | 0.630–1.545 | 0.952 | - | - | - | |||
| Myo | 1.009 | 0.975–1.045 | 0.605 | - | - | - | |||
| Age | 0.992 | 0.960–1.024 | 0.614 | 0.997 | 0.965–1.029 | 0.838 | 1.008 | 0.976–1.041 | 0.616 |
| Diabetes | 1.159 | 0.551–2.440 | 0.697 | 1.718 | 0.781–3.781 | 0.178 | 1.519 | 0.675–3.418 | 0.312 |
| cTnI | 6.809 | 2.760–16.796 | <0.001 | 6.217 | 2.548–15.619 | <0.001 | 4.878 | 2.026–11.747 | <0.001 |
| CARMN | 0.011 | 0.003–0.039 | <0.001 | - | - | - | 0.049 | 0.012–0.200 | <0.001 |
| LVEF | 0.879 | 0.841–0.919 | <0.001 | 0.900 | 0.859–0.942 | <0.001 | 0.910 | 0.868–0.954 | <0.001 |
| CK-MB | 2.491 | 1.893–3.278 | <0.001 | 2.198 | 1.597–3.023 | <0.001 | 1.823 | 1.334–2.491 | <0.001 |
BMI, body mass index; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Myo, myoglobin; cTnI, cardiac troponin I; CARMN, cardiac mesoderm enhancer-associated non-coding RNA; LVEF, left ventricular ejection fraction; CK-MB, creatine kinase-myocardial band.