Table 1.

Important studies on hepatic arterial buffer response, with main findings

Reference	Species	Main finding
Lautt (1985) [41]	Cat	Antagonism of HABR by the adenosine antagonist 8-phenyltheophylline
Lautt et al. (1988) [42]	Cat	Hepatic arterial vascular response to intravenous drugs dependent on direct action of the drug on hepatic artery and on indirect effects of drug-induced changes in portal venous blood flow
Lautt and McQuaker (1989) [43]	Cat	Protective dilatation of hepatic artery during haemorrhage is mediated by adenosine
Lautt et al. (1990) [44]	Cat	During high portal venous blood flow, hepatic artery is nearly fully constricted; during low portal venous blood flow, hepatic artery is nearly fully dilated
Henderson et al. (1992) [45]	Human	Intact HABR in liver transplant patients
Ayuse et al. (1994) [46]	Pig	Change in portal venous blood flow alters hepatic arterial resistance upstream from the site of a constant arterial back pressure
Ayuse et al. (1995) [47]	Pig	HABR is abolished during endotoxaemia independently of nitric oxide or α-adrenergic receptor antagonists

HABR = hepatic arterial buffer response. Adapted from Jakob [10].