Table 3.
Time to Treatment Events Among Patients with Newly Diagnosed and Established GAD
| Newly diagnosed GAD cohort N = 59 275 |
Established GAD cohort N = 86 920 |
|||
|---|---|---|---|---|
| Average (SD) | Median (IQR) | Average (SD) | Median (IQR) | |
| Time to first event (days) | ||||
| Discontinuation | 105 (87) | 84 (122) | 146 (99) | 119 (154) |
| Switching | 66 (71) | 31 (65) | 82 (90) | 42 (101) |
| Combination | 83 (83) | 49 (93) | 66 (81) | 32 (70) |
| Persistence | 621 (153) | 689 (275) | 641 (132) | 704 (197) |
| Time to second event (days) | ||||
| Discontinuation | 130 (140) | 90 (145) | 197 (174) | 129 (262) |
| Switching | 110 (160) | 38 (84) | 89 (145) | 29 (64) |
| Combination | 140 (147) | 87 (98) | 239 (215) | 147 (279) |
| Persistence | 133 (108) | 90 (128) | 109 (99) | 86 (134) |
| Duration of first gap (days) | ||||
| Discontinuation | 209 (166) | 146 (235) | 150 (126) | 96 (134) |
| Switching | 11 (41) | 1 (0) | 8 (30) | 1 (0) |
| Combination | 10 (41) | 1 (0) | 4 (22) | 1 (0) |
| Persistence | 58 (65) | 48 (81) | 29 (48) | 1 (50) |
Abbreviations: IQR, interquartile range; SD, standard deviation.