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. 2026 Oct 22;6:1917605. doi: 10.3389/fneph.2026.1917605

Figure 2.

Figure with five box plots labeled A to E compares urinary biomarker levels between female and male healthy volunteers (HV) and kindey transplant récipient (KTR), showing significantly lowers values.

Immunoblot analysis of NCC and pNCC in urinary exosomes of female and male populations of KTR and volunteers. KTR and HV were divided into male (M) and female (F). Both NCC (A) and pNCC (B) abundances were significantly lower in KTR when compared to HV in both male and female populations. Densitometric analyses of immunoblot for TSG101 (C) revealed that TSG101expression in KTR was significantly lower when compared to HV in both male and female populations. Therefore, NCC (D) and pNCC (E) abundances were normalized to TSG101 abundance. Dataset are presented as box plots with whiskers representing the 5th and the 95th percentile, N = 23 females for both KTR and HV. N = 35 males for both KTR and HV. Statistical significance was assessed using Kruskal-Wallis test. ****p < 0.000, ***p<0.001, **p<0.01 and *p<0.05.