Table 1.
Demographic, neuropsychological and fMRI task performance data
| ε3/ε3 (n = 17) | ε3/ε4 (n = 23) | |
| Age (years) | 52.1 (6.8) | 54.0 (5.6) |
| Age Range (years) | 42 – 65 | 43 – 65 |
| Education (years) | 15.9 (2.1) | 16.5 (2.6) |
| Gender Ratio: Female/Male | 11/6 | 13/10 |
| Handedness (% righthanded) | 94% | 96% |
| Homocysteine (μmol/l) | 8.2 (1.8) | 7.9 (1.5) |
| Blood Cholesterol (mg/dl) 1 | 215.8 (32.6) | 204.9 (31.4) |
| Hematocrit (mL/dl) | 40.0 (2.1) | 40.6 (2.6) |
| Hemoglobin (g/dl) | 13.8 (0.8) | 13.9 (0.9) |
| Systolic Blood Pressure (mmHg) | 131.5 (14.1) | 132.6 (17.8) |
| WASI Verbal IQ | 112.8 (8.6) | 113.6 (10.5) |
| WASI Performance IQ | 114.0 (8.4) | 111.9 (8.5) |
| WAIS-III Working Memory | 109.5 (14.5) | 104.4 (13.5) |
| COWAT adjusted raw score | 42.8 (10.9) | 47.1 (10.0) |
| Boston Naming Test | 56.6 (2.7) | 56.6 (1.8) |
| RAVLT total recall trials 1–5 | 54.0 (5.2) | 52.1 (7.5) |
| RAVLT short delay recall | 11.6 (2.6) | 11.0 (2.1) |
| RAVLT long delay recall | 11.7 (2.3) | 10.7 (2.9) |
| RAVLT recognition | 14.1 (1.2) | 14.0 (1.4) |
| Trail Making Test A (s) | 27.1 (6.0) | 27.0 (8.1) |
| Trail Making Test B (s) | 55.4 (19.7) | 67.0 (22.3)* |
| CES-D | 4.2 (4.4) | 4.1 (4.2) |
| Snodgrass Accuracy (%) | 99.1 (1.2) | 98.6 (2.2) |
| Snodgrass RT (sec) | 0.81 (0.2) | 0.89 (0.1) |
| Snodgrass Misses | 0.3 (0.8) | 0.7 (1.6) |
Data are presented as mean (SD). * denotes significant differences (p < 0.05) between the groups. WASI = Wechsler Abbreviated Scale of Intelligence, WAIS = Wechsler Adult Intelligence Scale, COWAT = Controlled Oral Word Fluency Test, RAVLT = Rey Auditory Verbal Learning Test, CES-D = Center for Epidemiological Studies – Depression Inventory. See text for further discussion of test measures. 1 = total non-fasting Blood Cholesterol