Table 3.
Incidence of hemophilic arthropathy by interval-level characteristics
| Number of analytic units | Joint-years of follow-up | Number of HA progression events | Incidence rate per 1,000 joint-years of follow-up | |||
|---|---|---|---|---|---|---|
| Interval-start Arnold–Hilgartner stage | Arnold–Hilgartner stage | 0 | 517 | 7,574 | 22 | 2.9 |
| I | 21 | 164 | 6 | 36.6 | ||
| II | 41 | 544 | 23 | 42.3 | ||
| III | 47 | 353 | 43 | 121.9 | ||
| Regular prophylaxis at first visit to our institute | No | 412 | 3,797 | 54 | 14.2 | |
| Yes | 456 | 4,837 | 40 | 8.3 | ||
| Laterality | Right | 295 | 4,280 | 52 | 12.1 | |
| Left | 288 | 4,354 | 42 | 9.6 | ||
Incidence of progression to hemophilic arthropathy, defined as reaching Arnold–Hilgartner stage ≥ IV. Values are shown by analytic characteristics. Observation intervals were created when treatment status or radiographic status changed; therefore, counts for interval-start Arnold–Hilgartner stage and prophylaxis status represent analytic intervals and do not equal the number of unique joints shown in Table 2. Laterality is shown at the joint level. Incidence rates are expressed per 1,000 joint-years of follow-up. HA, hemophilic arthropathy