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. 1992 Jan;33(1):115–117. doi: 10.1136/gut.33.1.115

Comparison of aspiration and scintigraphic techniques for the measurement of gastric emptying rates of liquids in humans.

E J Beckers 1, J B Leiper 1, J Davidson 1
PMCID: PMC1373876  PMID: 1740267

Abstract

A comparison was made of two techniques to measure the rate of gastric emptying. A noninvasive scintigraphic technique using a gammacamera and an invasive aspiration technique based on dye dilution were performed simultaneously. Seven healthy male volunteers each consumed two different liquid meals on two separate occasions. Scintigraphic measurements were performed continuously with aspiration every 10 minutes for a total of one hour. Gastric emptying rates were expressed as slope values after semilog linearisation of the emptying curves. Agreement between the two methods was assessed from the individual differences and mean of the two techniques, as well as from the geometric mean, including 95% limits of agreement. The scintigraphic technique gave a 70% slower emptying rate than the dye dilution technique. However, the 95% limits of agreement are large (1.56 to 0.30), reflecting the small sample size and the large coefficient of variation in the techniques used.

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Selected References

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  1. Avill R., Mangnall Y. F., Bird N. C., Brown B. H., Barber D. C., Seagar A. D., Johnson A. G., Read N. W. Applied potential tomography. A new noninvasive technique for measuring gastric emptying. Gastroenterology. 1987 Apr;92(4):1019–1026. [PubMed] [Google Scholar]
  2. Beckers E. J., Rehrer N. J., Brouns F., Ten Hoor F., Saris W. H. Determination of total gastric volume, gastric secretion and residual meal using the double sampling technique of George. Gut. 1988 Dec;29(12):1725–1729. doi: 10.1136/gut.29.12.1725. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bland J. M., Altman D. G. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986 Feb 8;1(8476):307–310. [PubMed] [Google Scholar]
  4. Christian P. E., Datz F. L., Sorenson J. A., Taylor A. Technical factors in gastric emptying studies. J Nucl Med. 1983 Mar;24(3):264–268. [PubMed] [Google Scholar]
  5. Christian P. E., Moore J. G., Sorenson J. A., Coleman R. E., Weich D. M. Effects of meal size and correction technique on gastric emptying time: studies with two tracers and opposed detectors. J Nucl Med. 1980 Sep;21(9):883–885. [PubMed] [Google Scholar]
  6. Collins P. J., Horowitz M., Cook D. J., Harding P. E., Shearman D. J. Gastric emptying in normal subjects--a reproducible technique using a single scintillation camera and computer system. Gut. 1983 Dec;24(12):1117–1125. doi: 10.1136/gut.24.12.1117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Elashoff J. D., Reedy T. J., Meyer J. H. Analysis of gastric emptying data. Gastroenterology. 1982 Dec;83(6):1306–1312. [PubMed] [Google Scholar]
  8. George J. D. New clinical method for measuring the rate of gastric emptying: the double sampling test meal. Gut. 1968 Apr;9(2):237–242. doi: 10.1136/gut.9.2.237. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Glowniak J. V., Wahl R. L. Patient motion artifacts on scintigraphic gastric emptying studies. Radiology. 1985 Feb;154(2):537–538. doi: 10.1148/radiology.154.2.3966143. [DOI] [PubMed] [Google Scholar]
  10. Goo R. H., Moore J. G., Greenberg E., Alazraki N. P. Circadian variation in gastric emptying of meals in humans. Gastroenterology. 1987 Sep;93(3):515–518. doi: 10.1016/0016-5085(87)90913-9. [DOI] [PubMed] [Google Scholar]
  11. HORTON R. E., ROSS F. G., DARLING G. H. DETERMINATION OF THE EMPTYING-TIME OF THE STOMACH BY USE OF ENTERIC-COATED BARIUM GRANULES. Br Med J. 1965 Jun 12;1(5449):1537–1539. doi: 10.1136/bmj.1.5449.1537. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. HUNT J. N., SPURRELL W. R. The pattern of emptying of the human stomach. J Physiol. 1951 Apr;113(2-3):157–168. doi: 10.1113/jphysiol.1951.sp004562. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Harvey R. F., Mackie D. B., Brown N. J., Keeling D. H., Davies W. T. Measurement of gastric emptying time with a gamma camera. Lancet. 1970 Jan 3;1(7636):16–18. doi: 10.1016/s0140-6736(70)90525-8. [DOI] [PubMed] [Google Scholar]
  14. Hunt J. N. A modification to the method of George for studying gastric emptying. Gut. 1974 Oct;15(10):812–813. doi: 10.1136/gut.15.10.812. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Jensen R. C., Warren B., Laursen C., Morrissey M. C. Static pre-load effect on knee extensor isokinetic concentric and eccentric performance. Med Sci Sports Exerc. 1991 Jan;23(1):10–14. [PubMed] [Google Scholar]
  16. Lawaetz O., Dige-Petersen H. Gastric emptying of liquid meals: validation of the gamma camera technique. Nucl Med Commun. 1989 May;10(5):353–364. doi: 10.1097/00006231-198905000-00006. [DOI] [PubMed] [Google Scholar]
  17. McClelland G. R., Sutton J. A. Epigastric impedance: a non-invasive method for the assessment of gastric emptying and motility. Gut. 1985 Jun;26(6):607–614. doi: 10.1136/gut.26.6.607. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Rehrer N. J., Beckers E., Brouns F., Hoor ten F., Saris W. H. Exercise and training effects on gastric emptying of carbohydrate beverages. Med Sci Sports Exerc. 1989 Oct;21(5):540–549. [PubMed] [Google Scholar]
  19. Sutton J. A., Thompson S., Sobnack R. Measurement of gastric emptying rates by radioactive isotope scanning and epigastric impedance. Lancet. 1985 Apr 20;1(8434):898–900. doi: 10.1016/s0140-6736(85)91674-5. [DOI] [PubMed] [Google Scholar]
  20. Tothill P., McLoughlin G. P., Heading R. C. Techniques and errors in scintigraphic measurements of gastric emptying. J Nucl Med. 1978 Mar;19(3):256–261. [PubMed] [Google Scholar]
  21. Tothill P., McLoughlin G. P., Holt S., Heading R. C. The effect of posture on errors in gastric emptying measurements. Phys Med Biol. 1980 Nov;25(6):1071–1077. doi: 10.1088/0031-9155/25/6/004. [DOI] [PubMed] [Google Scholar]

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