Table 4.

Sedatives used in status asthmaticus

Agents	Dose	Side effects
Peri-intubation period
Midazolam	1 mg (intravenous) slowly, every 2–3 min until the patient allows positioning and airways inspection	Hypotension, respiratory depression
Ketamine	1–2 mg/kg (intravenous) at a rate of 0.5 mg/kg/min	Sympaticomimetics effects, delirium
Propofol	60–80 mg/min initial intravenous infusion up to 2.0 mg/kg, followed by an infusion of 5–10 mg/kg/hour as needed	Respiratory depression
Mechanical ventilation
Midazolam	1–10 mg/hour continuous intravenous infusion
Morphine sulfate	1–5 mg/hour intravenous continuous infusion	Nausea, vomiting, ileus
Ketamine	0.1–0.5 mg/min (intravenous)
Propofol	1–4.5 mg/kg/hour (intravenous)	Seizures, hyperlipidemia