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The amount of pQBI PGK plasmid DNA [supercoiled (sc) and linear (li)] protected from Eco52I hydrolysis by different concentrations of conjugate 14. The amounts of uncleaved supercoiled and linear DNA are given as dark and light shaded bars, respectively: at 1000 nM conjugate 14, 100% sc, 100% li; at 500 nM, 47% sc, 100% li; at 250 nM, 38% sc, 61% li; at 100 nM, 22% sc, 39% li; at 50 nM, 0% sc, 30% li; at 10 nM, 0% sc, 0% li.
