Table 2.

Effect of MDL-A on IL-6 or LIF-induced differentiation of M1 cells on macrophage-like cells

Treatment	Population, %
	Nondifferentiated	Differentiated
Untreated	85.4  ± 4.6	11.3  ± 0.2
MDL-A, 70 μM	83.4  ± 7.7	15.1  ± 1.4
IL-6, 50 ng/ml	37.4  ± 5.3	61.4  ± 10.7
+ MDL-A, 70 μM	68.6  ± 5.1	30.4  ± 4.2
LIF (5 ng/ml)	36.8  ± 7.1	63.2  ± 11.2
+ MDL-A, 70 μM	40.7  ± 5.4	58.3  ± 9.3

M1 cells (5 × 10⁵ cell/250 μl per well) were seeded and incubated with or without 70 μM MDL-A in the presence or absence of 50 ng/ml rhIL-6 or 5 ng/ml rhLIF for 72 h. Values represent mean ± SE of three experiments. Statistical significance:

^*, P < 0.01 vs. corresponding control.