Table 2.

The EC₅₀ values of FMRFa peptides chirally modified in successive single residues for HEK-MrgC11 and HEK-MrgA1 cells

Peptides	MrgC11, nM	MrgA1, nM
F-M-R-Fa	114  ± 32	420  ± 71
(D)F-M-R-Fa	108  ± 1	882  ± 55
F-(D)M-R-Fa	11  ± 4	1,260  ± 223
F-M-(D)R-Fa	Inactive	Inactive
F-M-R-(D)Fa	Inactive	643  ± 80
R-Fa	460  ± 35	Inactive
R-F-OH	632  ± 124	Inactive

Data represent mean ± SEM from triplicate independent determinations.