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Known mutants
| αLeu91 | Leu91Pro |
| αPro124 | No mutants reported |
| βTrp37 | Trp37Ser, Trp37Arg, Trp37Gly |
| βGly46 | Gly46Arg, Gly46Glu (The predicted effect of these mutations is to decrease the stability of the β chain.) |
| βLeu96 | Leu96Val, Leu96Pro |
| βHis97 | His97Gln, His97Tyr, His97Pro, His97Leu |
| βPro124 | Pro124Arg, Pro124Ser, Pro124Gln, Pro124Leu |
| βHis146 | His146Arg, His146Leu, His146Asp, His146Pro, His146Gln, His146Tyr |
