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. 2002 Oct 22;99(23):14813–14818. doi: 10.1073/pnas.232389399

Fig 1.

Fig 1.

DE-cadherin and Arm in the interface between SSCs and IGS cells. (A) A cross-section diagram of a Drosophila germarium. (B) A confocal section of a germarium containing a marked lacZ+ SSC labeled for LacZ (red), Fas3 (green), and nuclei (blue). One marked lacZ+ SSC (arrow) is evident in the middle of germarium by its low Fas3 expression and the production of LacZ-positive follicle cells (one indicated by arrowhead). (C) A germarium containing two marked lacZ+ IGS cells labeled for LacZ (red), Fas3 (green), and nuclei (blue). Two lacZ+ IGS cells (arrows) with low levels of Fas3 expression are apparent, but LacZ-positive follicle cells are not present in the ovariole. (D and E) A germarium carrying a marked lacZ+ SSC labeled for DE-cadherin (green), LacZ (red), and nuclei (blue). (D) The SSC is identified by its location in the middle of the germarium and capacity to generate LacZ-positive follicle cells (one indicated by arrowhead). (E) The enlarged area (dotted rectangle shown in D) showing the existence of DE-cadherin-positive foci (arrowheads) between a marked lacZ+ SSC and neighboring IGS cells. (F and G) A germarium carrying a marked lacZ+ SSC labeled for Arm (green), LacZ (red), and nuclei (blue). (F) The SSC is identified by its location in the middle of the germarium and capacity to generate LacZ-positive follicle cells (one indicated by arrowhead). (G) The enlarged area (dotted rectangle shown in F) showing the existence of Arm-positive foci (arrowheads) between a marked SSC and neighboring IGS cells. CB, cystoblast; CPC, cap cell; DCs, developing cysts; FC, follicle cell; FS, fusome; SS = spectrosomes; TF = terminal filament cell. (Bars in B and C represent 10 μm.)